Pharmacological implications and emerging uses in clinical practice of Withania somnifera [Implicaciones farmacológicas y usos emergentes en la práctica clínica del Withania somnifera]
DOI:
https://doi.org/10.62574/2cfk7x68Keywords:
traditional medicine, psychological stress, neuroprotectionAbstract
Objective: To analyse the pharmacological implications and emerging uses of Withania somnifera in clinical practice. Method. Descriptive literature review in Google Scholar, Elsevier, SciELO and Medigraphic databases (2020-2025). Twenty articles were selected using Boolean descriptors and specific inclusion criteria. Results and Conclusion: Studies demonstrated a 27.9% reduction in cortisol levels, significant improvements in cognitive function, working memory and sleep quality. Anti-inflammatory effects were observed in arthritis, metabolic benefits in type 2 diabetes and improved physical performance. The effective dosage ranged from 300-1000 mg daily. Ashwagandha has neuroprotective, anxiolytic, and adaptogenic properties with a favourable safety profile. Larger-scale clinical studies are needed to establish optimal doses and definitive therapeutic recommendations.
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