Effect of buffered lidocaine injection with sodium bicarbonate in dental practice [Efecto de la inyección de lidocaína tamponada con bicarbonato de sodio en la práctica odontológica]

Authors

DOI:

https://doi.org/10.62574/g779zp20

Keywords:

buffered lidocaine, local anesthetics, pain management

Abstract

Objective: To identify the effects of sodium bicarbonate-buffered lidocaine injection in dental practice. Method: Descriptive study through a literature review of specialised primary sources. Research studies from the last six years were analysed using databases such as PubMed, NCBI, and Google Scholar. Results: Lidocaine combined with sodium bicarbonate, regardless of the mixing proportions, demonstrated beneficial clinical effects such as a significant reduction in pain during injection and acceleration of the onset of anaesthesia. Alkalisation of the pH using sodium bicarbonate raises the acidic pH of the anaesthetic to approximately 6.55-7.30, resembling the physiological pH of oral tissues. Conclusions: Sodium bicarbonate-buffered lidocaine is a convenient and safe method that reduces injection pain and accelerates the onset of anaesthetic effect without compromising the pharmacological properties of the drug.

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Published

2025-09-29

Issue

Section

Short originals

How to Cite

1.
Santana-Escobar JC, González-Cardona Y, Romero-Fernández AJ. Effect of buffered lidocaine injection with sodium bicarbonate in dental practice [Efecto de la inyección de lidocaína tamponada con bicarbonato de sodio en la práctica odontológica]. SRS [Internet]. 2025 Sep. 29 [cited 2026 Jul. 27];4(UNIANDES):113-20. Available from: https://revistasinstitutoperspectivasglobales.rperspectivasinvestigativas.org/index.php/sanitas/article/view/843